Supply and Support of Complete Antibody Quantification Testing Systems

Anti-D and Anti-c Antibody Quantification NHS Blood & Transplant (NHSBT) Red Cell Immunohaematology (RCI) function is seeking to engage with suppliers of red cell antibody quantification methods via an early market engagement exercise. Please note this is not the start of a procurement process; a separate contract notice will be published to cover this requirement.

Prior to commencing the formal procurement process, NHSBT would like to consult the market to improve our knowledge of all current offers available, identify further opportunities and potential issues, as well as gauge market interest in the proposed service. This engagement will help shape NHSBT procurement strategy.

The RCI laboratories in NHSBT provide a range of reference services to hospitals, focusing on ensuring safe and effective blood transfusions by diagnosing and managing complex issues related to red blood cells. Antibody (anti-D and anti-c) quantification is a vital component of RCI service, predominantly providing service to NHS hospitals.

The test results play a crucial role in guiding the clinical management of alloimmunised ANC patients’ by predicting the risk of haemolytic disease of the foetus and newborn and triggering referral to an FMU specialist, In addition, quantification is used to assist in the laboratory differentiation of immune anti-D from passive anti-D Ig This specialised test conducted in 4 of the 7 RCI laboratories (namely Birmingham, Colindale, Liverpool and Newcastle). RCI processes approximately 10,000 tests annually.

The test is vital for identifying levels of alloimmune and prophylactic anti-D, as well as alloimmune anti-c in obstetric and other referrals. NHSBT is seeking to engage with suppliers on the market who can provide Antibody Quantification. The requirement is likely to include the following: • Quantification of anti-D and anti-c (expressed in IU/mL). • Less than 24-hour TAT • Quality requirements (such as CE marked) As part of the early market engagement exercise, NHSBT would like to discuss our requirement with suppliers along with a time frame for supply.