Invitation to tender for the supply of licensed tenofovir disoproxil / emtricitabine combined tablet formulations for the PrEP IMPACT Trial

This procurement will be conducted by AGCSU on behalf of NHS England Specialised Commissioning. Any contract arising from this procurement will be between the successful Provider and NHS England (National Health Service Commissioning Board).

The successful Provider will be awarded the contract included within the tender documents This procurement relates to the supply of licensed tenofovir disoproxil / emtricitabine combined tablet formulations (the Goods) for the PrEP IMPACT Trial. The Supplier appointed as a result of this procurement will be responsible for the supply and delivery of the Goods in accordance with the Specification and Contract, to Trial Sites recruited in to the trial.

The PrEP IMPACT Trial is anticipated to include at least 10,000 participants over three years via up to 200 Trial Sites in order to develop a properly evidence-based public health policy for the subsequent use and recommendations for the administration of PrEP. In recognition that the objectives of the PrEP IMPACT Trial include determining the take up and use of Goods by Participants; the Authority reserves the right to amend: • The number of Trial Sites; and/or • The number of Participants; and/or • Other parameters of the PrEP IMPACT Trial; and/or • The processes to manage the PrEP IMPACT Trial so as to manage the overall costs of the PrEP IMPACT Trial within the allocated budget of £10m.

The proposed procurement will focus solely on the supply of the Goods to the PrEP IMPACT Trial and will be completely independent of, and have no bearing on, any subsequent procurement for the supply of licensed tenofovir disoproxil / emtricitabine combined tablet formulations to any future commissioned service and treatment of HIV. The Contracting Authority intends to use the 'Arden and Greater East Midlands CSU e-Procurement Portal' in this procurement exercise.

Further details are available on the Bravo e-tendering portal: https://ardengemcsu.bravosolution.co.uk. The ITT deadline is 12:00 noon on 26/06/17 Additional information: NHS Arden & GEM CSU is managing this Procurement in accordance with the Public Contracts Regulations 2015 (the "Regulations").

The Contracting Authority will be using an eTendering system in this procurement exercise. Suppliers Instructions on how to Express Interest in this Tender: 1.

Register your company on the eSourcing portal (this is only required once) -Browse to the eSourcing Portal: https://ardengemcsu.bravosolution.co.uk and click the link to register - Accept the terms and conditions and click 'continue' - Enter your correct business and user details - You will shortly receive an e-mail with your unique password (please keep this secure) 2. Express an Interest in the tender - Login to the portal with the username/ password - Click the 'PQQs / ITTs Open To All Suppliers' link. (These are Pre- Qualification Questionnaires or Invitations to Tender open to any registered supplier) - Click on the relevant ITT (ITT_732) to access the content. - Click the 'Express Interest' button at the top of the page. - This will move the PQQ /ITT into your 'My PQQs/ My ITTs' page.